Safe & Effective GLP-1 Injections: Fast Weight Loss Treatments
Compare Top Providers: Explore the best fit for your budget and weight loss goals.
- Access: 24/7 unlimited clinician visits with no waitlists.
- Flexibility: Both injectable and oral GLP-1 options available.
- Offer: First month for just $149 (regularly $299+).
- Speed: 24-hour shipping and a 20% weight loss success guarantee.
- Clinical: Direct access to board-certified physicians and fast approvals.
- Offer: Save $130 off your first month (starting at $69).
- Support: Dedicated insurance concierge to handle all prior authorizations.
- Approach: Comprehensive 12-month metabolic health curriculum and coaching.
- Offer: First month for $45 (membership cost only).
- Variety: Custom oral medication kits for needle-free weight loss.
- Pricing: Flat-rate, transparent monthly pricing with no insurance needed.
- Offer: Start for as low as $69/month with long-term plans.
- Behavior: Psychology-based program pairing GLP-1s with habit tracking.
- Fitness: Includes Muscle Defense™ workouts to preserve lean muscle mass.
- Offer: Clinical trial membership for as low as $69.
- Holistic: Unlimited access to doctors, dietitians, and fitness apps.
- Stability: Fixed pricing that stays the same even as your dosage increases.
- Offer: Save $100 off any plan
- Access: 24/7 unlimited clinician visits with no waitlists.
- Flexibility: Both injectable and oral GLP-1 options available.
- Offer: First month for just $149 (regularly $299+).
Editor’s Top 3
Choosing the Right Weight Loss Program? Here are some things to consider…
With millions of Americans seeking effective long-term weight management solutions, finding the right medical support is critical. The best weight loss injection or program for you will depend on many factors, including your medical history, your BMI, and your specific metabolic health goals.
While this decision should always be made during a consultation with a licensed healthcare provider, it is important to understand the different clinical approaches and platforms available to you. When evaluating telehealth providers, here are the key factors to consider so you can find the right medical support for your needs:
Are Weight Loss Medications Effective?
Yes. Modern prescription weight loss medications, particularly GLP-1 agonists like semaglutide (Wegovy) and tirzepatide (Zepbound), have shown significant clinical effectiveness. Unlike older diet pills, these medications work by mimicking natural hormones to regulate appetite and slow digestion.
Clinical trials and real-world data highlight the following results:
Significant Weight Reduction: On average, patients using semaglutide lose about 15% of their body weight over 68 weeks. Those using tirzepatide often see even higher results, averaging a 20–22.5% reduction over 72 weeks.
Beyond the Scale: These medications are also effective at improving “cardiometabolic” health, including lowering blood pressure, improving cholesterol levels, and reducing the risk of major cardiovascular events like heart attacks or strokes.
Comparison to Lifestyle Alone: In major studies, patients using these medications alongside diet and exercise lost significantly more weight than those using lifestyle changes and a placebo (who typically lost only about 2–3%).
Important Considerations: While highly effective, these medications are intended for long-term chronic weight management. Most patients find that maintaining weight loss requires staying on the medication or following a strict clinical maintenance plan, as weight regain is common if the treatment is stopped without medical supervision.
Popular Weight Loss Medications
Ozempic® (Semaglutide)
Ozempic® is an FDA-approved weekly injection specifically designed to treat type 2 diabetes. Its active ingredient, semaglutide, mimics the GLP-1 hormone naturally produced in the gut. According to Dr. Rekha Kumar, Chief Medical Officer at Found, this hormone regulates weight by signaling fullness to the brain and slowing stomach emptying. While it is highly effective for weight loss and reducing cardiovascular risks, Ozempic® is technically only FDA-approved for diabetes management, though it is frequently used off-label for weight loss.
Wegovy® (Semaglutide)
Wegovy® utilizes the same active ingredient as Ozempic® (semaglutide) but is specifically FDA-approved for chronic weight management. It is prescribed for adults with a BMI of 30 or higher, or those with a BMI of 27 who have at least one weight-related medical condition (such as high blood pressure or type 2 diabetes). Like its counterpart, Wegovy® is administered as a convenient once-weekly injection.
Saxenda® (Liraglutide)
While also a GLP-1 receptor agonist, Saxenda® uses the active ingredient liraglutide. It is FDA-approved for adults with a BMI of 30+ (or 27+ with comorbidities) and for adolescents aged 12 and older weighing over 132 pounds. Saxenda® works by suppressing appetite and prolonging feelings of fullness. Unlike the weekly semaglutide options, Saxenda® requires a daily injection to remain effective.
Weight Loss Injections vs. Fat Burning Pills
How to Choose the Best Weight Loss Medication for You
Choosing a weight loss medication is a personal decision that should be made in partnership with a healthcare provider. Because these are long-term medical treatments, the “best” option depends on your health profile, lifestyle, and preferences.
When discussing options with your doctor, consider these four key factors:
Your Health Goals and BMI: Most medications are approved for adults with a BMI of 30+ (obesity) or a BMI of 27+ (overweight) with at least one weight-related condition like high blood pressure or type 2 diabetes. Some medications, like Tirzepatide (Zepbound), have shown higher average weight loss percentages in clinical trials compared to others.
Administration Preference: Consider how the medication fits into your routine. Are you comfortable with a weekly self-injection (Wegovy, Zepbound), or would you prefer a daily injection (Saxenda)? There are also oral options like Orlistat or Mysimba for those who prefer tablets over needles.
Side Effect Tolerance: Most GLP-1 medications (injections) cause temporary gastrointestinal side effects like nausea or constipation as your body adjusts. If you have a history of specific issues—such as pancreatitis or certain thyroid conditions—some medications may be ruled out entirely.
Insurance and Cost: This is often the deciding factor. Coverage for weight loss medications varies wildly between insurance plans. Some telehealth platforms offer compounded versions or help navigate “Prior Authorization” to make branded medications more affordable.
†Ozempic® (semaglutide) is a prescription-only subcutaneous injection that has not been approved by the FDA as safe and effective to treat obesity and overweight; however, studies have shown that it may be associated with weight loss in individuals with type 2 diabetes.
††Wegovy® (semaglutide) is a prescription-only subcutaneous injection that helps to reduce excess body weight and maintain weight reduction in adults with obesity and adults with overweight and at least one weight-related condition.
†††Zepbound® (tirzepatide) is a prescription-only subcutaneous injection that, when combined with a reduced-calorie diet and exercise, helps to reduce excess body weight and maintain weight reduction in adults with obesity or overweight and at least one weight-related condition, as well as moderate to severe obstructive sleep apnea in adults with obesity.
††††Generic Liraglutide (liraglutide injection) is a prescription-only subcutaneous injection that, as an adjunct to diet and exercise, helps to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus.